{"id":5467,"date":"2021-09-01T07:23:06","date_gmt":"2021-09-01T07:23:06","guid":{"rendered":"https:\/\/givelegacy.com\/?p=5467"},"modified":"2023-06-14T13:06:54","modified_gmt":"2023-06-14T13:06:54","slug":"oligospermia-causes-diagnosis-treatment-and-more","status":"publish","type":"post","link":"https:\/\/www.givelegacy.com\/resources\/oligospermia-causes-diagnosis-treatment-and-more\/","title":{"rendered":"Oligospermia: causes and treatment for low sperm count"},"content":{"rendered":"<hr>\n<p><span style=\"font-weight: 400;\">Around 8\u201312% of couples worldwide experience difficulty <a href=\"https:\/\/www.givelegacy.com\/mens-guide-to-trying-to-conceive\/\">conceiving<\/a>, referred to as infertility. Of those couples, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4691969\/\"><span style=\"font-weight: 400;\">40\u201350%<\/span><\/a><span style=\"font-weight: 400;\"> struggle with male factor infertility, which could be caused by sperm-related conditions such as oligospermia (low sperm count) and <\/span><a href=\"https:\/\/givelegacy.com\/resources\/azoospermia-symptoms-diagnosis-treatment\/\"><span style=\"font-weight: 400;\">azoospermia<\/span><\/a><span style=\"font-weight: 400;\"> (zero sperm count).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hearing &#8220;infertility&#8221; and &#8220;low sperm count&#8221; can feel disheartening, as if having biological children is impossible. But that&#8217;s not true. There are many ways you can pave a path towards parenthood, even if you are diagnosed with oligospermia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this guide, we&#8217;ll cover everything you need to know about oligospermia: causes, diagnosis, treatment methods, and more.&nbsp;<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Takeaways:<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Those with oligospermia are still able to conceive, though conception may be more difficult or take longer.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oligospermia is often diagnosed through a semen analysis. Once diagnosed, further testing may be necessary to understand the root cause.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lifestyle factors \u2014 like smoking, drinking, diet, and exposure to chemicals and toxins \u2014 can increase a person\u2019s risk of oligospermia.&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oligospermia treatment methods will vary depending on the cause of your oligospermia.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">What is oligospermia?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Oligospermia, also known as oligozoospermia, is when a person&#8217;s sperm count falls below the World Health Organization&#8217;s (WHO) classification for healthy sperm counts: 15 million sperm per milliliter of semen. In simple terms, oligospermia is characterized by low sperm count and can have an impact on your ability to conceive naturally.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Depending on your sperm count, you may be diagnosed with a case of mild, moderate, or severe oligospermia:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Mild oligospermia<\/b><span style=\"font-weight: 400;\">: 10\u201315 million sperm per mL of semen.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Moderate oligospermia<\/b><span style=\"font-weight: 400;\">: 5\u201310 million sperm per mL of semen.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Severe oligospermia<\/b><span style=\"font-weight: 400;\">: 0\u20135 million sperm per mL of semen.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Aspermia or <\/b><a href=\"https:\/\/givelegacy.com\/resources\/azoospermia-symptoms-diagnosis-treatment\/\"><b>azoospermia<\/b><\/a><span style=\"font-weight: 400;\">: Absence of sperm in semen.<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">How low sperm count affects male fertility<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Having a lower sperm count doesn&#8217;t completely rule out the possibility of naturally conceiving, but it does decrease your chances of conception.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Fertilization is a \u201crace to the top\u201d of the female reproductive system, from the vagina to the fallopian tubes, where sperm meet the egg and fertilization occurs. In a healthy person without oligospermia, anywhere between 80 and 300 million sperm cells are released per ejaculation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, most are eliminated along the way. Any abnormal or otherwise defective sperm are likely to die on this journey, along with a good percentage of healthy sperm. In fact, less than 1 in a million from the original ejaculate will reach the egg at the time of fertilization. That\u2019s why it\u2019s important to start with a high number of sperm, and why low sperm count can affect conception.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pregnancy rates have been shown to increase as sperm count increases. A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/590540\/#:~:text=Pregnancy%20rates%20of%20approximately%2050,rates%20increased%20to%20above%2070%25.\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> observed that the average pregnancy rate of couples in which the male partner had a sperm count between 5 and 60 million\/mL was 50%. The pregnancy rate increased to 70% in couples with average sperm counts over 60 million\/mL.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16669917\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> that observed 308 men with oligospermia concluded that those with a sperm count of over 2 million sperm per mL of semen had a 22.1% chance of natural conception,&nbsp; provided that other sperm parameters were normal. Alternatively, in cases where sperm count was less than 2 million per mL of semen, natural conception became rare (1.6%).<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How is oligospermia diagnosed?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The primary diagnostic test for oligospermia is a <\/span><a href=\"https:\/\/givelegacy.com\/sperm-analysis\/\"><span style=\"font-weight: 400;\">semen analysis<\/span><\/a><span style=\"font-weight: 400;\">. During a semen analysis, a sample of semen is examined by a lab scientist under a microscope, to determine sperm count as well as <a href=\"https:\/\/www.givelegacy.com\/sperm-quality\/\">sperm quality<\/a>. Two abnormal semen analyses in a row are typically required to diagnose a condition like oligospermia or azoospermia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For the most part, a person will never realize they have oligospermia until they begin trying to conceive and experience difficulty. However, proactive <a href=\"https:\/\/www.givelegacy.com\/sperm-testing-guide\/\">sperm testing<\/a> can make this process more efficient. Instead of waiting it out in the unknown, there&#8217;s the option of ordering an <\/span><a href=\"https:\/\/givelegacy.com\/sperm-analysis\/\"><span style=\"font-weight: 400;\">at-home semen analysis kit<\/span><\/a><span style=\"font-weight: 400;\">. With Legacy, you can schedule a virtual appointment with a fertility specialist who will review your results and answer your questions.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">See our <\/span><\/i><a href=\"https:\/\/givelegacy.com\/sperm-testing-guide\/\"><i><span style=\"font-weight: 400;\">guide to sperm testing<\/span><\/i><\/a><i><span style=\"font-weight: 400;\">.<\/span><\/i><\/p>\n<h2><span style=\"font-weight: 400;\">What causes oligospermia?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It&#8217;s natural for <a href=\"https:\/\/www.givelegacy.com\/what-is-sperm\/\">sperm<\/a> count to fluctuate throughout your life, especially <\/span><a href=\"https:\/\/givelegacy.com\/resources\/age-limit-on-male-fertility\/\"><span style=\"font-weight: 400;\">as you age<\/span><\/a><span style=\"font-weight: 400;\">. But there are also conditions and lifestyle factors that can increase a person&#8217;s risk of oligospermia.&nbsp;<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Varicocele<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Enlarged veins within the scrotum, known as varicocele, can create oxidative stress, disrupt proper blood flow to the testes, or lower testosterone production \u2014 all factors that can negatively impact sperm count. <\/span><a href=\"https:\/\/givelegacy.com\/resources\/varicocele-and-male-fertility\/\"><span style=\"font-weight: 400;\">Varicocele<\/span><\/a><span style=\"font-weight: 400;\"> is fairly common, affecting roughly 15% of men. Varicocele usually develops during puberty and often goes unnoticed, since symptoms are typically mild.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Exposure to heat<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Exposure to heat can create oxidative stress, which has been <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4737001\/\"><span style=\"font-weight: 400;\">shown<\/span><\/a><span style=\"font-weight: 400;\"> to cause damage to sperm. Heat stress \u2014 from sitting for long periods of time every day, placing laptops or other heat-producing devices near your genitals, using saunas or hot tubs, or wearing tight clothing \u2014 is correlated to a decrease in sperm count, motility, and viability.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Exposure to toxins and radiation<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Exposure to radiation and to substances like pesticides, lead, metals, and petrochemicals can negatively impact sperm count. People who work in high-risk environments where they are regularly exposed to these dangers have been shown to have <\/span><a href=\"https:\/\/www.fertstert.org\/article\/S0015-0282(03)01188-9\/pdf\"><span style=\"font-weight: 400;\">lower sperm count and quality<\/span><\/a><span style=\"font-weight: 400;\">. If you work in the military or the agriculture, herbicides, plastic production, tobacco processing, or welding industries (among others), you may be at greater risk of developing low sperm count.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Sexually transmitted infections (STIs)<\/span><\/h3>\n<p><a href=\"https:\/\/givelegacy.com\/resources\/stis-stds-sperm-health-fertility\/)\"><span style=\"font-weight: 400;\">STIs can cause fertility issues<\/span><\/a><span style=\"font-weight: 400;\"> such as oligospermia. An active bacterial infection or virus can negatively impact your reproductive system, even if you don&#8217;t experience any symptoms. For example, HPV \u2014 the most common STI \u2014 has been shown to impact sperm production, even though it does not cause symptoms in many men. In one <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6681313\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\">, 75% of men who tested positive for HPV had abnormal semen analysis results, compared to only 44% of men who tested negative for HPV. It&#8217;s important to get tested regularly and get treated immediately if you test positive for an STI.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Hormone imbalance<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There are many <\/span><a href=\"https:\/\/givelegacy.com\/resources\/the-hormones-that-drive-male-fertility\/\"><span style=\"font-weight: 400;\">hormones that drive male fertility<\/span><\/a><span style=\"font-weight: 400;\">, like testosterone, follicle-stimulating hormone, and luteinizing hormone. These and a few other hormones play a key role in sperm production. If there&#8217;s an imbalance in any of these hormones, that could lower your sperm count (along with other sperm health parameters).<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Idiopathic oligospermia<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In some cases, a causative factor may not be found for low sperm count, which is referred to as \u201cidiopathic oligospermia.\u201d (Idiopathic means we don\u2019t know the root cause.) When a cause cannot be found, it can be difficult to recommend treatment to increase sperm count. Generally, making healthy lifestyle changes can help <\/span><a href=\"https:\/\/givelegacy.com\/sperm-improvement-guide\/\"><span style=\"font-weight: 400;\">improve sperm<\/span><\/a><span style=\"font-weight: 400;\">, along with your overall state of health. If that doesn&#8217;t help with fertilization, assisted reproductive technologies, like intracytoplasmic sperm injection (ICSI), have been <\/span><a href=\"https:\/\/academic.oup.com\/jcem\/article\/98\/3\/873\/2536497\"><span style=\"font-weight: 400;\">shown<\/span><\/a><span style=\"font-weight: 400;\"> to provide promising success rates.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How to treat oligospermia and increase sperm count<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Treatment methods for oligospermia will vary depending on your case.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>If a varicocele is the cause of your oligospermia<\/b><span style=\"font-weight: 400;\">, you may need surgery to close off enlarged veins to redirect blood flow to the testes.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>If a hormone imbalance is detected<\/b><span style=\"font-weight: 400;\">, you may require hormone treatments to restore a healthy balance and improve sperm production.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>If you have a bacterial infection or virus<\/b><span style=\"font-weight: 400;\">, then you may need a round of medication (like antibiotics) to clear the infection and inflammation. Depending on how far along the infection is, the medication may not help improve sperm count but can prevent even greater drops in sperm count.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>In most cases<\/b><span style=\"font-weight: 400;\">, including when you have a case of idiopathic oligospermia, you may be able to increase sperm count by making healthy lifestyle changes.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Getting pregnant with oligospermia<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In some cases, the treatment methods outlined above can only do so much. I<\/span><span style=\"font-weight: 400;\">f you have oligospermia and have not been able to conceive on your own, <a href=\"https:\/\/www.givelegacy.com\/future-fertility-treatments\/\">fertility treatments<\/a> can help.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Intrauterine insemination (IUI): <\/b><span style=\"font-weight: 400;\">This is a fertility treatment where sperm is washed (processed) and placed directly into a patient&#8217;s uterus. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7558391\/\"><span style=\"font-weight: 400;\">Studies<\/span><\/a><span style=\"font-weight: 400;\"> show that IUI can provide an improved pregnancy rate for those with mild to moderate oligospermia. Although pregnancy rates tend to be lower when using IUI compared to IVF and ICSI, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5591588\/#:~:text=The%20lowest%20pregnancy%20rate%20achieved,of%20assisted%20reproduction%20%5B17%5D.\"><span style=\"font-weight: 400;\">data <\/span><\/a><span style=\"font-weight: 400;\">supports IUI as an effective, simple, and low-cost treatment. Because IUI is one of the least invasive and least expensive assisted reproductive techniques, it&#8217;s a good first-line treatment option before attempting more invasive or costly methods.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>In vitro fertilization (IVF): <\/b><span style=\"font-weight: 400;\">This technique involves removing oocytes from the ovary and combining them with sperm to facilitate fertilization outside of the body. Once fertilized, the embryo is transferred into the uterine cavity. IVF <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3922320\/\"><span style=\"font-weight: 400;\">success rates<\/span><\/a><span style=\"font-weight: 400;\"> can vary depending on the age of the female partner, but one <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5591588\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> found that among men with oligospermia, IVF resulted in the highest pregnancy rate.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Intracytoplasmic sperm injection (ICSI): <\/b><span style=\"font-weight: 400;\">This is a treatment method where a single live sperm is injected directly into an egg. One <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5591588\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> reports a pregnancy rate of 36.4% for people with oligospermia. For people who experience low sperm count because of an obstructive cause (like those with <\/span><a href=\"https:\/\/givelegacy.com\/resources\/azoospermia-symptoms-diagnosis-treatment\/\"><span style=\"font-weight: 400;\">obstructive azoospermia<\/span><\/a><span style=\"font-weight: 400;\">), ISCI can be a promising assisted reproductive technique.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Remember, it&#8217;s possible to conceive with oligospermia. The first step towards a plan of action is <\/span><a href=\"https:\/\/givelegacy.com\/sperm-analysis\/\"><span style=\"font-weight: 400;\">getting a semen analysis<\/span><\/a><span style=\"font-weight: 400;\">. From there, you can choose treatment methods or explore <\/span><a href=\"https:\/\/givelegacy.com\/resources\/how-to-increase-sperm-count\/\"><span style=\"font-weight: 400;\">ways to increase sperm count<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Around 8\u201312% of couples worldwide experience difficulty conceiving, referred to as infertility. Of those couples, 40\u201350% struggle with male factor infertility, which could be caused by sperm-related conditions such as oligospermia (low sperm count) and azoospermia (zero sperm count). Hearing &#8220;infertility&#8221; and &#8220;low sperm count&#8221; can feel disheartening, as if having biological children is impossible. [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":15791,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"none","_seopress_titles_title":"%%post_title%% %%sep%% %%sitetitle%%","_seopress_titles_desc":"%%post_excerpt%%","_seopress_robots_index":"","footnotes":""},"categories":[61,114,230,98,35,105],"tags":[89,13,173,256,196],"class_list":["post-5467","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infertility","category-male-fertility-basics-understanding-male-health","category-male-factor-infertility","category-testing-sperm","category-understanding-male-health","category-male-fertility-basics-testing-sperm","tag-low-sperm-count","tag-male-factor-infertility","tag-oligospermia","tag-oligozoospermia","tag-sperm-concentration"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/5467"}],"collection":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5467"}],"version-history":[{"count":1,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/5467\/revisions"}],"predecessor-version":[{"id":16146,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/5467\/revisions\/16146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/media\/15791"}],"wp:attachment":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}