{"id":15213,"date":"2020-03-17T14:19:48","date_gmt":"2020-03-17T14:19:48","guid":{"rendered":"http:\/\/legacy.varunme.com\/resources\/steroids-and-sterility-a-new-study\/"},"modified":"2023-06-14T15:25:58","modified_gmt":"2023-06-14T15:25:58","slug":"steroids-and-sterility-a-new-study","status":"publish","type":"post","link":"https:\/\/www.givelegacy.com\/resources\/steroids-and-sterility-a-new-study\/","title":{"rendered":"New study highlights potential impact of steroids, including 90% chance of fertility damage"},"content":{"rendered":"<p class=\"\" data-pm-slice=\"0 0 []\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\"><em>4 minute read <\/em><\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">Many men choose a structured workout routine to stay in shape, <a href=\"https:\/\/www.menshealth.com\/fitness\/a19534499\/10-muscle-building-tips\/\">building muscle<\/a> and cutting fat \u2013 all in a quest to sculpt a more attractive figure while also boosting overall health.<\/p>\n<p class=\"arx-block-focus\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">And it doesn\u2019t hurt that potential partners tend to take note when a man gets serious about working out. <a href=\"https:\/\/www.psychologytoday.com\/us\/blog\/dating-and-mating\/201701\/why-physical-attraction-matters-and-when-it-might-not\">Physical beauty<\/a> certainly isn\u2019t the only factor that people look for when searching for a mate, but it\u2019s almost always where they begin.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">To enhance one\u2019s chances of maximizing a first impression, some men decide to use anabolic steroids to enhance the benefits of lifting weights. These substances have long been the focus of oversight by governing bodies in professional sports, where the drugs have been banned, with some users forfeiting awards and titles that they won years before their drug use was discovered \u2013 even when, in the case of <a href=\"https:\/\/www.independent.co.uk\/news\/science\/performance-enhancing-drug-epo-lance-armstrong-tour-de-france-seven-titles-not-work-study-a7816181.html\">cyclist Lance Armstrong<\/a>, his steroid of choice turned out not to be ineffective.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\"><strong>The link between steroids and fertility<\/strong><\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">Now, though, a new study says that the health consequences of using anabolic steroids include a 90 percent chance of damage to a man\u2019s fertility. The information can be found in a letter published in the <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/joim.12884\"><em>Journal of Internal Medicine<\/em><\/a> (paywall site).<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">The co-authors of the letter, Dr. James Mossman at Brown University in Providence, Rhode Island and&nbsp;<a href=\"https:\/\/www.sheffield.ac.uk\/oncology-metabolism\/staff\/pacey\" target=\"_blank\" rel=\"noopener noreferrer\">Professor Allan Pacey<\/a>&nbsp;at the University of Sheffield (Professor Pacey is also a member of <a href=\"https:\/\/givelegacy.com\/team\">Legacy\u2019s advisory board<\/a>), say that the risks posed to fertility by steroids are similar to those brought about by medications designed to prevent hair loss, specifically finasteride, which alters the manner in which testosterone is metabolized.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\"><a href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-1548-167\/finasteride-oral\/finasteride-oral\/details\">Finasteride<\/a> has also been known to reduce sperm counts as well as hamper <a href=\"https:\/\/www.givelegacy.com\/sperm-quality\/\">sperm motility<\/a> (swimming ability). Another side effect of taking the drug is erectile dysfunction.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">The new discovery, dubbed an \u201cevolutionary paradox\u201d by an article published in <a href=\"https:\/\/www.bionews.org.uk\/page_143095\"><em>BioNews 1000<\/em><\/a>, is now known as the Mossman-Pacey paradox \u2013 so called because men who take them in order to become more attractive wind up harming their chances of starting a family.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\"><a href=\"https:\/\/www.brown.edu\/academics\/ecology-and-evolutionary-biology\/sites\/academics-ecology-and-evolutionary-biology\/files\/Mossman_2014.pdf\">Dr. Mossman<\/a> first took note of the link between steroid use and impaired fertility when he was studying to obtain his doctorate from the University of Sheffield.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">\u201cI noticed some men coming in to have their fertility tested and these guys were huge. They are trying to look really big, to look like the pinnacles of evolution,\u201d he said. \u201cBut they are making themselves very unfit in an evolutionary sense, because without exception they had <a href=\"https:\/\/www.webmd.com\/infertility-and-reproduction\/guide\/azoospermia-causes-treatment#1\">no sperm in their ejaculation<\/a> at all\u201d.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">Professor Pacey was quoted by <a href=\"https:\/\/www.earth.com\/news\/men-less-fertile-attractive\/\">Earth.com<\/a> as saying, \u201cIsn\u2019t it ironic that men go to the gym to look wonderful, for the most part to attract women, and inadvertently decrease their fertility\u201d.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">In speaking to the <a href=\"https:\/\/www.bbc.com\/news\/health-48396071\">BBC<\/a>, Professor Pacey commented, \u201cThe irony is one thing, but I think the key message is for fertility patients. It keeps cropping up in clinics and the message is not getting out to young men that it&#8217;s a problem and a bit of info could save them a lot of heartache.\u201d<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\"><strong>Knowing the direct effects<\/strong><\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">Anabolic steroids, which are synthetic versions of testosterone, work by tricking the brain\u2019s pituitary gland into believing that a man\u2019s testes are working overtime. As a result, the glands respond by ceasing the production of a pair of hormones \u2013 known as <a href=\"https:\/\/www.webmd.com\/a-to-z-guides\/luteinizing-hormone-test#1\">Luteinizing Hormone<\/a> (LH) and <a href=\"https:\/\/www.webmd.com\/women\/fsh-test#1\">Follicle-Stimulating Hormone<\/a> FSH \u2013 which happen to be the critical hormones responsible for the creation of <a href=\"https:\/\/www.givelegacy.com\/what-is-sperm\/\">sperm<\/a>.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">According to Professor Pacey, roughly 9 in 10 anabolic steroid users \u201care likely to become <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/male-sterility\">sterile<\/a>\u201d. He went on to say that, while baldness is less predictable, sales of hair loss-prevention products \u201care going through the roof and that makes it an increasingly common problem\u201d.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">Dr. Mossman pointed out that taking vanity-based medications could wind up turning a man into something of an \u201cevolutionary dud\u201d. It is not on par with, say, the displaying of a <a href=\"https:\/\/www.theguardian.com\/science\/2017\/may\/19\/a-peacocks-tail-how-darwin-arrived-at-his-theory-of-sexual-selection\">peacock\u2019s tail<\/a>, which has the effect of making males more desirable to females, while also increasing the possibility of passing along genes to succeeding generations.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">While it is true that some bird species participate in <a href=\"https:\/\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.2002965\">cooperative breeding<\/a> \u2013 where some don\u2019t have their own offspring but instead help raise descendants of relatives \u2013 Dr. Mossman says that humans are likely the only creatures known to harm their own fertility by trying to make themselves attractive to the opposite sex.<\/p>\n<p class=\"\" data-arx-type=\"paragraph\" data-arx-first-level=\"true\">All the more reason to <a href=\"https:\/\/givelegacy.com\/sperm-freezing\">proactively store your sperm<\/a> now \u2013 before taking up a steroid-enhanced exercise regimen, or even resorting to medications to limit hair loss. To store your best assets, it is recommended to start with <a href=\"https:\/\/givelegacy.com\/sperm-testing-guide\/\">sperm testing<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Many men choose a structured workout routine to stay in shape, building muscle and cutting fat \u2013 all in a quest to sculpt a more attractive figure while also boosting overall health. The use of steroids to enhance looks can cause sterility more often than not.<\/p>\n","protected":false},"author":14,"featured_media":482,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"none","_seopress_titles_title":"%%post_title%% %%sep%% %%sitetitle%%","_seopress_titles_desc":"%%post_excerpt%%","_seopress_robots_index":"","footnotes":""},"categories":[8,9],"tags":[144,145,108,53,171,32],"class_list":["post-15213","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-fertility-research","tag-bodybuilding","tag-exercise","tag-fertility-science","tag-lifestyle","tag-steroids","tag-testosterone"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/15213"}],"collection":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15213"}],"version-history":[{"count":1,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/15213\/revisions"}],"predecessor-version":[{"id":17666,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/posts\/15213\/revisions\/17666"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/media\/482"}],"wp:attachment":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15213"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}