{"id":9401,"date":"2022-03-25T19:34:48","date_gmt":"2022-03-25T23:34:48","guid":{"rendered":"https:\/\/www.givelegacy.com\/?post_type=glossary&#038;p=9401"},"modified":"2023-05-05T12:04:23","modified_gmt":"2023-05-05T12:04:23","slug":"unexplained-infertility","status":"publish","type":"glossary","link":"https:\/\/www.givelegacy.com\/vnext\/fertility-glossary\/unexplained-infertility\/","title":{"rendered":"Unexplained infertility"},"content":{"rendered":"\n<p>Unexplained or idiopathic infertility is a condition defined by a lack of obvious cause behind a couple&#8217;s or individual&#8217;s infertility. Unexplained infertility can only be diagnosed after both partners have been completely evaluated with common fertility issues being ruled out. Unexplained infertility accounts for about 15\u201330% of all infertility cases.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What is unexplained infertility?<\/h2>\n\n\n\n<p>Unexplained infertility \u2014 also referred to as idiopathic <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/infertility\/\">infertility<\/a> in medical settings \u2014 is when tests, lab results, and other findings are unable to find a cause for a couple&#8217;s inability to get pregnant. Although it&#8217;s hard to say exactly what percentage of infertility cases are unexplained, some research suggests that approximately <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4322174\/#:~:text=30%25%20of%20infertile%20couples%20worldwide,women%20above%2035%20years%20of\">30% of infertility cases<\/a> have unknown causes.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Unexplained infertility vs. male-factor infertility<\/h2>\n\n\n\n<p>When a couple is trying to get pregnant, there are two factors at play: female factor \u2014 the health of the eggs and female reproductive system \u2014 and <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/male-factor-infertility\/\">male factor<\/a>, the health of the <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/sperm\/\">sperm<\/a> and male reproductive system.<\/p>\n\n\n\n<p>If a person with testes is experiencing poor semen parameters (low <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/sperm-count\/\">sperm count<\/a>, <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/motility\/\">motility<\/a>, <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/morphology\/\">morphology<\/a>, or genetic health) or has sexual dysfunction that makes conception difficult, that\u2019s considered male-factor infertility. Typically, doctors will try to find the cause of the issue. This may be hormonal imbalances, an infection or inflammatory condition, a genetic disease, or exposure to harmful environmental or lifestyle factors that negatively impact sperm production.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Diagnosing unexplained infertility<\/h2>\n\n\n\n<p>When a couple is unable to become pregnant after 12 months or trying (or six months if over the age of 35), it is usually recommended that they see a <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/fertility-specialist\/\">fertility doctor<\/a>. A fertility evaluation is completed along with standard tests for both partners, including a <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/semen-analysis-sa\/\">semen analysis<\/a>, blood tests to evaluate <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/hormone\/\">hormone<\/a> levels, and imaging tests (such as an <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/sonogram-ultrasound\/\">ultrasound<\/a>).<\/p>\n\n\n\n<p>If all evaluations and testing come back normal, but you\u2019re still unable to get pregnant on your own, you may be diagnosed with unexplained infertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Treatments for unexplained infertility<\/h2>\n\n\n\n<p>Unexplained infertility can be disheartening, but this diagnosis doesn&#8217;t mean having a biological child is impossible. Couples with unexplained infertility can try fertility medications and procedures like <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/intrauterine-insemination-iui\/\">intrauterine insemination (IUI) <\/a>and <a href=\"https:\/\/www.givelegacy.com\/fertility-glossary\/in-vitro-fertilization-ivf\/\">in vitro fertilization (IVF)<\/a>, which can improve pregnancy rates.<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":0,"template":"glossary","glossary-cat":[],"class_list":["post-9401","glossary","type-glossary","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/glossary\/9401"}],"collection":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/types\/glossary"}],"author":[{"embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/users\/14"}],"version-history":[{"count":1,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/glossary\/9401\/revisions"}],"predecessor-version":[{"id":17259,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=\/wp\/v2\/glossary\/9401\/revisions\/17259"}],"wp:attachment":[{"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9401"}],"wp:term":[{"taxonomy":"glossary-cat","embeddable":true,"href":"https:\/\/www.givelegacy.com\/vnext\/index.php?rest_route=%2Fwp%2Fv2%2Fglossary-cat&post=9401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}